A key question in biology is how multi-cellular organisms generate their shape. In plants, an interplay between growth, patterning, and differentiation within mechanically connected tissue determine the diversity of organ forms. Although the genetic basis of organogenesis is extensively studied, our understanding of how molecular instructions are translated into biological shapes is fragmentary. Linking genes with geometries require precise measurements of growth dynamics and gene expression in developing organs over time.

Daniel Kierzkowski

The lab aims to understand how small groups of undifferentiated cells give rise to the variety of organ form by uncovering the molecular, cellular, and tissue level mechanisms controlling organogenesis. Our expertise in growth tracking, 3D-image analysis, genetics, and biomechanics is applied to dissect how biological forms are generated during development. Our long-term goal is to integrate these different aspects of development into comprehensive models of organogenesis. We hope that our research will pave the way toward a unified understanding of the development and diversification of form in multicellular organisms essential for future improvements of economically important crops.


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